Spontaneous subgaleal haematoma with severe headache in two children during acute painful sickle cell crisis
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Keywords
Abstract
Sickle cell disease is an inherited disorder of haemoglobin formation, predominantly affecting individuals of African, Indian, or Mediterranean descent. Acute painful episodes frequently occur in these patients due to the blockage of small blood vessels by sickled cells, leading to tissue infarction. Two children of Nigerian descent, presented with severe headaches during a painful crisis episode with associated swelling on their scalps. CT imaging in both cases showed subgaleal haematoma which was managed conservatively in addition to managing the painful crisis with a good outcome. This report highlights the clinical presentation, diagnostic approach, and management of this uncommon complication of sickle cell anaemia.
References
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11. Foula MS, Hassan A, AlQurashi A, Alsaihati A, Sharroufna M. Spontaneous subgaleal hematoma in a patient with sickle cell disease: A case report and literature review. Clin Case Rep. 2019 Oct 9;7(11):2220-2224. doi: 10.1002/ccr3.2435. PMID: 31788283; PMCID: PMC6878059.
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2. Komarla R, Soares BP, Chern JJ, Milla SS. Spontaneous epidural hematoma secondary to bone infarction in sickle cell anaemia: case report. J Neurosurg Pediatr. 2018;22:18-21. doi:10.3171/2018.1.peds17407.
3. Arends S, Coebergh JA, Kerkhoffs JL, van Gils A, Koppen H. Severe unilateral headache caused by skull bone infarction with epidural haematoma in a patient with sickle cell disease. Cephalalgia. 2011 Sep;31(12):1325-8. doi: 10.1177/0333102411414441. Epub 2011 Jul 29. PMID: 21803935.
4. Page C, Gardner K, Height S, Rees DC, Hampton T, Thein SL. Nontraumatic extradural hematoma in sickle cell anemia: a rare neurological complication not to be missed. Am J Hematol. 2014 Feb;89(2):225-7. doi: 10.1002/ajh.23579. Epub 2013 Sep 30. PMID: 24038013.
5. Alqurashi MM, Raslan OM, Gmati GE. Spontaneous Subgaleal Hematoma in a Sickle Cell Disease Patient: A Case Report. J Med Cases. 2020 Feb;11(2):46-48. doi: 10.14740/jmc3433. Epub 2020 Feb 28. PMID: 34434360; PMCID: PMC8383627.
6. National Institute for Health and Care Excellence. Sickle cell disease: managing acute painful episodes in hospital (CG143) [Internet]. 2012 [cited 2024 May 18]. Available from: https://www.nice.org.uk/guidance/cg143/chapter/Recommendations
7. Gonçalves JS, Tribovane D, Pires M, Lopes RS, de Oliveira MRI, Inacio-Conceição C, et al. Cranial Masses in Sickle Cell Disease. J Pediatr. 2022 Apr;243:228-30.
8. Joy J, Vasnaik MA, Bhat V, Anandram S, George A. Spontaneous Epidural Hematoma in Sickle Cell Crisis: A Case Report. Cureus. 2022 Apr 26;14(4):e24492. doi: 10.7759/cureus.24492. PMID: 35651401; PMCID: PMC9134707.
9. Mishra SS, Senapati SB, Gouda AK, Behera SK, Patnaik A. Spontaneous extradural and subgaleal hematoma: A rare neurosurgical crisis of sickle cell disease. Asian J Neurosurg. 2017;12(1):47-50.
10. Kavanagh PL, Sprinz PG, Vinci SR, Bauchner H, Wang CJ. Management of children with sickle cell disease: a comprehensive review of the literature. Pediatrics. 2011 Aug;128(3):e586-93. doi: 10.1542/peds.2010-3253. PMID: 21873549.
11. Foula MS, Hassan A, AlQurashi A, Alsaihati A, Sharroufna M. Spontaneous subgaleal hematoma in a patient with sickle cell disease: A case report and literature review. Clin Case Rep. 2019 Oct 9;7(11):2220-2224. doi: 10.1002/ccr3.2435. PMID: 31788283; PMCID: PMC6878059.
12. DeBaun MR, Kirkham FJ. Central nervous system complications and management in sickle cell disease. Blood. 2016 Mar 17;127(7):829-38. doi: 10.1182/blood-2015-09-618579. PMID: 26637701.
