Validation of Siriraj stroke Scoring System in the Clinical Differentiation of stroke Sub-types in a resource Limited setting
Main Article Content
Keywords
Siriraj stroke scoring system,, Validation, Resource limited setting
Abstract
Background: Stroke remains one of the major non-communicable public health disease conditions with resultant high morbidity and mortality. Neuroimaging in the form of Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) is adjudged to be the most reliable and efficient method of accurately diagnosing stroke and ruling out differentials. However, in view of cost implication and non-availability, a clinical scoring system known as the Siriraj Stroke Score (SSS) was developed to clinically differentiate stroke types, especially in resource-limited settings. This study sought to validate and determine the role of Siriraj stroke score in the clinical evaluation of patients presenting with acute stroke.
Methodology: This is a descriptive prospective study that was conducted over a one-year period. The study populations were adult patients presenting with acute stroke in a tertiary health facility in North-Western Nigeria. Clinical details with neuroimaging in the form of a CT scan were obtained. Data obtained was analyzed using Stata 15.
Result: Fifty-four percent (54%) of patients enrolled were males and ischaemic stroke is the commonest stroke subtype present in 69% of patients studied. Altered levels of consciousness, headache and vomiting are important discriminatory variables of the scoring system. The sensitivity, specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV) and accuracy of Siriraj Stroke Score for haemorrhagic stroke is 92%, 72%, 62%, 95% and 62% respectively.
Conclusion: Siriraj Stroke Score with sensitivity greater than 90% is reliable in differentiating the stroke sub-types; the patients in the ‘grey zone’ will however require neuroimaging.
References
2. Ekeh B, Ogunniyi A, Isamade E EU. Stroke mortality and its predictors in a Nigerian teaching hospital. Afr Health Sci. 2015;15(1):74–81.
3. Ogun SA, Oluwole S, Aogunseyinde O, O Fatade A, Ojini F, A Odusote K. Accuracy of the Siriraj stroke score in differentiating cerebral haemorraghe and infarction in African Nigerians. Vol. 20, African Journal of Neurological Sciences. 2001; 20(1)
4. Feigin VL, Norrving B, Mensah GA. Global Burden of Stroke. Circ Res. 2017;120(3):439-448.
5. Pandey RP, Pandey A IM. A comparative Study of Clinical Scoring System of Cerebrovascular Accident with CT Scan. Indian Pract. 2015;68(8):22–30.
6. Hameed M, Aziz T, Feroze J. Correlation of clinical and CT scan diagnosis of stroke. Pakistan J Med Heal Sci. 2012;6(3):786–788.
7. Poungvarin N, Viriyavejakul A, Komontri C. Siriraj stroke score and validation study to distinguish supratentorial intracerebral haemorrhage from infarction. Br Med J. 1991;302 (679): 565-567.
8. Truelsen T, Begg S, Mathers C. The global burden of cerebrovascular disease. Glob Burd Dis. 2000;1–67.
9. Ogbole GI, Owolabi MO, Ogun O, Ogunseyinde OA, Ogunniyi A. Time of Presentation of Stroke Patients for Ct Imaging in a Nigerian Tertiary Hospital. Ann Ibadan Postgrad Med. 2015;13(1):23–28.
10. Nyandaiti YW, Bwala SA. Validation study of the siriraj stroke score in North-East Nigeria. Niger J Clin Pract. 2008;11 (3):176-180.
11. Chukwuonye II, Ohagwu KA, Uche EO, Chuku A, Nwanke RI, Ohagwu CC, et al. Validation of siriraj stroke score in southeast Nigeria. Int J Gen Med. 2015; 8:349-353.
12. Kolapo KO, Ogun SA, Danesi MA, Osalusi BS, Odusote KA. Validation study of the Siriraj stroke score in African Nigerians and evaluation of the discriminant values of its parameters: A preliminary prospective CT scan study. Stroke. 2006;37(8): 1997-2000.
13. Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM, et al. ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina11This document was approved by the American College of Cardiology Board of Trustees in March 1999, the American Heart Association Science Advisory and Coordinating Committee. J Am Coll Cardiol. 1999; 33(7):2092-2197.
14. Araoye MO. Research Methodology with Statistics for Health and Social Sciences. Second. Ibadan Nigeria: Ibadan Nathadex Publishers; 2004; 117–119 .
15. Balarabe SA KJ. Relative Frequencies of Neurological Disorders in Northwestern Nigeria: A Prospective Study. Ann Afr Med. 2019;18(2):5.
16. Johnson W, Onuma O, Owolabi M, Sachdev S. Stroke: A global response is needed. Bulletin of the World Health Organization. 2016.
17. Nyodu T, Singh KB, Kenny S, Singh J, Singh CD, Singh Mk. A comparison of clinical diagnosis with Computed Tomography findings in stroke patients. J Med Soc. 2013;27(3):216-221.
18. Singh H, Gupta JB, Gupta MS, Aggarwal R. Assessment of the utility of Siriraj Stroke Score (SSS) in stroke patients of Pt. BD Sharma PGIMS hospital, Rohtak, India. Med J Indones. 2001;10(3):164-168.
19. Badam P, Solao V, Pai M, Kalantri SP. Poor accuracy of the Siriraj and Guy’s hospital stroke scores in distinguishing haemorrhagic from ischaemic stroke in a rural, tertiary care hospital. Natl Med J India. 2003;16(1):8-12.
20. Kochar DK, Joshi A, Agarwal N, Aseri S, Sharma B V., Agarwal TD. Poor diagnostic accuracy and applicability of Siriraj stroke score, Allen score and their combination in differentiating acute haemorrhagic and thrombotic stroke. J Assoc Physicians India. 2000;48(2);584-588.
21. Wadhwani J, Hussain R, Raman PG. Nature of lesion in cerebrovascular stroke patients: Clinical stroke score and computed tomography scan brain correlation. J Assoc Physicians India. 2002;50(6):777-781
22. Hung LY, Wang PY, Wang Y, Chia LG. Clinical distinction between acute hemorrhagic and acute ischemic stroke by Siriraj stroke score. Zhonghua Yi Xue Za Zhi (Taipei). 1995;55(3):248-252
23. Hui ACF, Wu B, Tang ASY, Kay R. Lack of clinical utility of the Siriraj Stroke Score. Intern Med J. 2002;32(7): 311-314.
24. Soman A, Joshi SR, Tarvade S, Jayaram S. Greek stroke score, siriraj score and Allen score in clinical diagnosis of intracerebral hemorrhage and infarct: Validation and comparison study. Indian J Med Sci. 2004;58(10):417–422.
25. Celani MG, Righetti E, Migliacci R, Zampolini M, Antoniutti L, Grandi CF, et al. Comparability and validity of two clinical scores in the early differential diagnosis of acute stroke. BMJ. 1994;308(6945):1674.
26. Nouira S, Boukef R, Bouida W, Marghli S, Dridi Z, Benamou S,et al. Accuracy of Two Scores in the Diagnosis of Stroke Subtype in a Multicenter Cohort Study. Annals of emergency medicine. 2009;53 (3):373-378.
27. Akpunonu BE, Mutgi AB, Lee L, Khuder S, Federman DJ, Roberts C. Can a clinical score aid in the early diagnosis and treatment of various stroke syndromes? Am J Med Sci. 1998;315(3):194-198.
28. Hawkins GC, Bonita R, Broad JB, Anderson NE. Inadequacy of clinical scoring systems to differentiate stroke subtypes in population-based studies. Stroke. 1995;26(8):1338-1340.
29. Zenebe G, Asmera J, Alemayehu M. How accurate is siriraj stroke score among Ethiopians? A brief communication. Ethiop Med J. 2005;43(1):35-38.
30. Somasundaran A, Mohammed H, Kezhukatt J, George AT, Potty SN. Accuracy of Siriraj stroke scale in the diagnosis of stroke subtypes among stroke patients. Int J Res Med Sci. 2017;5(3):1084.
31. Jamal Q, Rahman AS, Razzaque S, Siddiqui MA, Ara J, Altaf A. Comparison of siriraj stroke score with computerized tomography in establishing the type of the stroke among Pakistani population. Eur J Gen Med. 2015;12(3):234-238.
32. Connor MD, Modi G, Warlow CP. Accuracy of the Siriraj and Guy’s Hospital Stroke Scores in urban South Africans. Stroke. 2007;38(1):62-68.
33. Salawu F, Umar I, Danburam A. Comparison of two hospital stroke scores with computerized tomography in ascertaining stroke type among Nigerians. Ann Afr Med. 2009;8(1):14-18.
34. Panchal N, Khokhar N, Mathur D. Study of the prevalence of stroke and its correlation with siriraj score & radio imaging with outcome of patients. International Journal and Applied Medical Sciences. 2015;5(2):150–155.
35. Abisheik M.B, Kulkarni A, Anil Kumar T, Vishwanath K. Validation of Siriraj Stroke Score in Patients Presenting With Acute Cerebrovascular Accidents. J Evid Based Med Healthc. 2018;5(48):3327–3330.
36. Huang JA, Wang PY, Chang MC, Chia LG, Yang DY, Wu TC. Allen score in clinical diagnosis of intracranial hemorrhage. Zhonghua Yi Xue Za Zhi (Taipei). 1994;54(6):407-411.