Correlation between oligohydramnios and anaemia in the third trimester of pregnancy: A study in a tertiary care hospital in Pakistan.

Main Article Content

asma batool
Mussarat
Zaiba
Saadia
Ayesha
Nida Faisal

Keywords

anaemia, oligohydramnios, correlation

Abstract

Background: Maintaining normal amniotic fluid index and normal hemoglobin level is crucial for normal fetal development. Their reduction can lead to maternal and fetal morbidity in the form of operative delivery and poor perinatal outcome such as, low birth weight. There is an association between oligohydramnios and anaemia, although there is scarcity on this correlation in literature. Early detection of oligohydramnios can improve maternal and perinatal outcome. This study aimed to investigate the association between oligohydramnios and anaemia during the third trimester of pregnancy.


Methodology: This retrospective cohort study was conducted at NESCOM Hospital, Pakistan. The study spanned from August 1, 2021, to July 31, 2022.


Results: The study included 109 pregnant individuals with oligohydramnios, resulting in an incidence of 22% among the total of 551 deliveries during the study period. The average age of participants was 29.75 years. The average gestational age was 33.52 weeks, with a range of 28 to 38 weeks. The analysis indicated that 44.03% of cases with oligohydramnios were associated with anaemia, followed by idiopathic causes (41.28%). Pearson's correlation revealed a significant association between oligohydramnios and anaemia (r = 0.307, p = 0.001), supporting the hypothesis of a potential interconnection between these two conditions. Regarding delivery outcomes, 81.6% underwent cesarean section, emphasizing the need for careful management in cases of oligohydramnios and anaemia. Neonatal outcomes indicated that 1.8% and 44.5% of neonates were extremely low birth weight and low birth weight, respectively.


Conclusion: This study provides empirical evidence supporting a significant association between oligohydramnios and anaemia in the third trimester.

Abstract 127 |

References

1- Sreelakshmi U, Bindu T, Subhashini T, Impact of oligohydramnios on maternal perinatal outcome: a comparative study, Int J Reprod contracept obstet gynecol 2018; 7(8): 3205-10.

2- James, Andra H. MD, MPH. Iron Deficiency Anemia in Pregnancy. Obstetrics & Gynecology 138(4):p 663-674, October 2021. | DOI: 10.1097/AOG.0000000000004559

3- Figueroa, L., McClure, E.M., Swanson, J. et al. Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries. Reprod Health 17, 19 (2020). doi.org/10.1186/s12978-020-0854

4- Twesigomwe, G., Migisha, R., Agaba, D.C. et al. Prevalence and associated factors of oligohydramnios in pregnancies beyond 36 weeks of gestation at a tertiary hospital in southwestern Uganda. BMC Pregnancy Childbirth 22, 610 (2022). doi.org/10.1186/s12884-022-04939-x

5- Black, R.E.; Allen, L.H.; Bhutta, Z.A.; Caulfield, L.E.; de Onis, M.; Ezzati, M.; Mathers, C.; Rivera, J.; Maternal and Child Undernutrition Study Group. Maternal and child undernutrition: Global and regional exposures and health consequences. Lancet 2008, 371, 243–260.

6- World Bank. Prevalence of Anemia among Children (% of Children Ages 6–59 Months). 2021. Available online: data.worldbank.org/indicator/SH.ANM.CHLD.ZS (accessed on 8 March 2023).

7- Jagatia K, Singh N, Patel S. Maternal and fetal outcome in oligohydramnios: A study of 100 cases. Int J Med Sci Public Health. 2013;2(3):724–7.

8- Rabie N, Magann E, Steelman S, Ounpraseuth S. Oligohydramnios in complicated and uncomplicated pregnancy: a systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2017;49(4):442–449. doi: 10.1002/uog.15929.

9- Sultana S, Akbar Khan M, Khanum Akhtar K, Aslam M. Low amniotic fluid index in high-risk pregnancy and poor apgar score at birth. J Coll Physicians Surg Pak. 2008;18(10):630–634.

10- Soren R, Maitra N, Patel PK, Sheth T. Elective versus emergency caesarean section: maternal complications and neonatal outcomes. IOSR J Nurs Health Sci. 2016;5(5):2320. .